Tell us about a time when you were able to work independently to achieve a research objective.

Sample answer to the question

During my previous role as a research assistant, I had the opportunity to work independently to achieve a research objective. We were investigating the effects of a specific gene mutation on cancer development. My task was to analyze the expression levels of multiple genes in tumor samples. I designed and executed the experiments, which involved RNA extraction, cDNA synthesis, and qPCR analysis. I carefully followed the protocols and ensured that all samples were processed accurately. I analyzed the data using statistical software and prepared a detailed report with my findings. My work allowed the team to identify a gene signature associated with aggressive cancer behavior. This experience demonstrated my ability to work independently, manage complex experiments, and contribute to important research outcomes.

A more solid answer

During my previous role as a research assistant, I was able to work independently to achieve a research objective. Our project aimed to investigate the role of a specific gene in autism spectrum disorder. My task was to perform gene expression analysis on brain tissue samples from individuals with and without the gene mutation. I developed a detailed experimental plan, including sample collection, RNA extraction, cDNA synthesis, and qPCR analysis. I worked meticulously, ensuring the accuracy of every step and recording all data meticulously. After analyzing the data, I identified significant differences in gene expression between the two groups, which provided valuable insights into the gene's function in autism. I presented my findings at team meetings and collaborated with other researchers to interpret the results. This experience showcased my ability to work independently, apply molecular biology techniques, and contribute to the understanding of complex genetic disorders.

Why this is a more solid answer:

The solid answer expands on the basic answer by providing more details about the project and specifying the gene of interest, autism spectrum disorder. It also highlights the candidate's ability to develop a detailed experimental plan, present findings at team meetings, and collaborate with other researchers. However, it can be improved by further emphasizing the candidate's ability to work as part of a team and communicate effectively, which are important skills for the Genomics Technician role.

An exceptional answer

During my previous role as a research assistant, I successfully completed a project by working independently to achieve a research objective. The project focused on investigating the genetic basis of a rare neurodevelopmental disorder. My task was to identify potential disease-causing variants in the genomes of affected individuals. I executed the project by utilizing cutting-edge genomics techniques, including DNA library preparation, sequencing, and bioinformatics analysis. I managed the entire process independently, from sample collection to data interpretation. I collaborated with bioinformaticians to analyze the sequencing data and identify rare variants with potential functional consequences. I presented my findings at international conferences and co-authored a publication in a renowned scientific journal. This experience demonstrated my ability to work independently, utilize advanced genomics techniques, and contribute to the scientific community's understanding of rare genetic disorders.

Why this is an exceptional answer:

The exceptional answer further enhances the solid answer by emphasizing the candidate's ability to utilize cutting-edge genomics techniques, collaborate with bioinformaticians, present findings at international conferences, and co-author a publication. It also highlights their contribution to the scientific community's understanding of rare genetic disorders. However, it can still be improved by adding more details about their teamwork and communication skills, as well as their ability to follow protocols and maintain a clean and organized lab environment.

How to prepare for this question

Review your previous research experiences and identify a project where you worked independently to achieve a research objective. Think about the specific techniques or experiments you performed.
Familiarize yourself with the basic genetics and molecular biology concepts relevant to the role.
Refresh your knowledge and practical skills in laboratory techniques such as PCR, gel electrophoresis, and DNA extraction.
Practice explaining your research project in a clear and concise manner, highlighting your role and contributions.
Reflect on any challenges or obstacles you faced during the project and how you overcame them.
Consider examples of how you communicated and collaborated with team members or presented your findings in a scientific setting.

What interviewers are evaluating

Ability to work independently
Understanding of basic genetics and molecular biology concepts
Familiarity with laboratory techniques
Record keeping and attention to detail