Can you describe your experience with laboratory techniques and operating scientific equipment?

Sample answer to the question

Absolutely, I've worked in a few labs over the past couple of years since I got my degree. For instance, during my final year project, I used a spectrophotometer for assessing sample purity and a centrifuge for separating mixtures. I've also got hands-on experience with pipetting, both manual and electronic, which was essential during my internship where we did a lot of liquid handling for assays. I'm pretty comfortable in a lab setting, and I'm always careful to follow safety protocols when operating any equipment.

A more solid answer

During my Master's program in Biochemistry, I honed my skills in laboratory techniques extensively. I frequently operated analytical equipment such as HPLCs for peptide sequencing and GC-MS for volatile organic compound analysis. My thesis research required the use of flow cytometry to analyze cell populations, which involved meticulous calibration and data interpretation. Organizationally, I managed a busy schedule, juggling multiple projects and ensuring accurate data logging, which was critical in maintaining the integrity of our findings. Moreover, being part of a diverse team, I regularly collaborated with chemists and biologists, which enhanced our project outcomes through interdisciplinary insights.

Why this is a more solid answer:

This solid answer goes further than the basic answer by specifying the types of scientific equipment used (HPLCs, GC-MS, flow cytometry) and the context in which they were utilized (Master's program, thesis research). It also touches on organizational skills by mentioning juggling multiple projects and maintaining accurate data logs. Furthermore, it reflects on teamwork in a multidisciplinary environment. However, it could still be improved by fleshing out the context of the projects, discussing challenges faced and overcome, and how the candidate stays current with laboratory techniques, which is vital for a Research Scientist role.

An exceptional answer

In my recent role as a lab technician, I not only mastered standard practices such as titration and PCR but also advanced techniques like CRISPR gene editing and single-cell RNA-Seq. Operating complex equipment, such as next-generation sequencers and confocal microscopes, became second nature to me. For example, while working on a cancer research project, I managed the entire DNA sequencing workflow - from sample preparation to data analysis using bioinformatics tools. This experience sharpened my organizational abilities, as I simultaneously coordinated with multiple departments to maintain efficient workflow and strict adherence to deadlines. My proactive engagement in laboratory team meetings and contributions to refining experimental protocols significantly improved our lab's efficiency and accuracy. Our team's findings were intricate to a publication in a peer-reviewed journal, to which I contributed both data and co-authored the paper, highlighting my written communication skills.

Why this is an exceptional answer:

The exceptional answer delves into specific laboratory techniques, such as PCR, CRISPR, and single-cell RNA-Seq, demonstrates mastery in operating advanced equipment, and contextualizes the experience with a real-world project. It also addresses the critical competencies of organizational skills, multitasking, collaboration, and communication implied in the job description. It shows the candidate's impact on lab efficiency and their contribution to published work, demonstrating a strong alignment with the responsibilities of a Research Scientist. This response instills confidence in the candidate's ability to fulfill the job role successfully.

How to prepare for this question

Reflect on your comprehensive laboratory experiences and select instances that showcase your use of complex equipment and techniques. Make sure these examples highlight your technical skills and problem-solving abilities.
Think about past situations where you've had to multitask or adhere to strict deadlines in a lab environment. Describe how you successfully managed these situations and what tools or methods helped you stay organized.
Consider times you have collaborated with a multidisciplinary team and recall specific contributions you made that led to successful outcomes. This demonstrates your team spirit and ability to work in a diverse environment.
Prepare an anecdote involving the maintenance and operation of advanced laboratory equipment, and how following safety protocols was integrated into your routine, to show your responsibility and attention to detail.
Stay updated on recent publications in your field and be ready to discuss how you actively engage with current research to continue learning and developing professionally.

What interviewers are evaluating

Strong scientific and technical aptitude
Familiarity with laboratory techniques and equipment
Organizational skills and attention to detail
Capability to multitask and meet deadlines in a fast-paced environment
Ability to work collaboratively in a multidisciplinary team environment